Duchenne muscular dystrophy (DMD) is a neuromuscular disease causing progressive skeletal muscle weakness and fatigue. The research team led by Associate Professor Hidetoshi Sakurai (Department of ...

Building functional human muscle in the laboratory has long been a goal of regenerative medicine, but one stubborn obstacle remains: real muscle is not just a mass of cells. Its strength and function ...

A new 3D model shows that Duchenne gene therapy can repair muscle fibers but fails to shut down the signals that drive scarring.

As we age, the muscles we rely on for daily activities tend to become less reliable. With enough decline, even normal movements such as getting out of bed become risky. Low muscle mass in the ...

Scientists at the University of California, Irvine’s School of Pharmacy & Pharmaceutical Sciences have discovered how muscle stem cells “flip a switch” to rebuild damaged muscle - a finding that could ...

Two related studies published today in Nature Metabolism show that a specialized intracellular recycling mechanism—chaperone-mediated autophagy (CMA)—is essential for muscle health. Subscribe to our ...

Swallowing is a fundamental human function that supports nutrition and communication. Damage to swallowing muscles can reduce ...