Relapsing after quitting cocaine is not simply a matter of willpower — it reflects physical changes in the brain, according to new research. Scientists have found that repeated cocaine use reshapes ...

An analysis of 2.2 million people reveals both shared and substance-specific genetic pathways for addiction risk, showing ...

Does using alcohol, nicotine, or cannabis engender addiction by changing the structure of brains, or does the structure of brains incline some people toward using those substances? In standard brain ...

At 17, he started his long journey through addiction treatment units. Now 22, he has been treated numerous times in the psychiatric unit of his local hospital for bipolar disorder, dual diagnosis, and ...

When considering the drugs most likely to cause former addicts to repeatedly relapse, opioids, cocaine, and methamphetamine ...

Remarkable scientific progress over the past five decades has helped us develop knowledge of how drugs of abuse induce pleasure, reinforce use, and lead to the compulsive self-administration we call ...

Cocaine addiction isn’t simply a failure of willpower — it’s the result of lasting biological changes in the brain.

Researchers have used mouse models to study how cocaine addiction alters the brain, illuminating why relapse is common as ...

It has long been known as the arbiter of reward in the brain, but recent findings could upend this classic theory of dopamine ...

To explore these neural differences, the researchers used a computational approach called “network control theory” to measure how the brain transitions between different patterns of activity during ...