Recent advances in computational biology have revolutionised the field of protein structure and function prediction. Traditionally, determining the three‐dimensional architecture of a protein from its ...

A new LMU study shows how proteins function reliably even without a stable 3D structure—and the crucial importance not only of short sequence motifs, but also of chemical characteristics.

The genomes of phages—viruses that infect bacteria—are largely composed of "dark matter": genes that encode proteins whose functions remain unknown. Less than four years ago, a team led by Prof. Rotem ...

For years, biomolecular condensates were thought to be simple, liquid-like droplets with little internal organization. New ...

On Wednesday, the Nobel Committee announced that it had awarded the Nobel Prize in chemistry to researchers who pioneered major breakthroughs in computational chemistry. These include two researchers ...

Protein activity can be precisely regulated via subtle changes in temperature using heat-sensitive switches. Underlying this capability is a novel modular design strategy developed by researchers at ...

A new LMU study shows how proteins function reliably even without a stable 3D structure – and the crucial importance not only of short sequence ...

David Baker, Demis Hassabis and John M. Jumper shared the Nobel Prize in Chemistry on Wednesday for their work on protein structure. Atila Altuntas / Anadolu via Getty Images On Wednesday morning, ...

In Greek mythology, Proteus, son of Poseidon and prophetic shepherd of sea-beasts, could foretell the future. The elusive sea god was difficult to capture as he assumed many forms—a lion, a serpent, ...

In genetics, one harmful variant can be enough to cause disease—but two can make it far more severe. One notable example is KJ, an infant diagnosed with a rare urea cycle disorder with a grim ...