R-loops are three-stranded nucleic acid structures that are abundant and widespread across the genome and that have important physiological roles in many nuclear processes. Their accumulation is ...

Fig. 3: Long-range R-loop dynamics are governed by the 6 bp periodicity of the crRNA–target strand hybrid. After locking, the R-loop length became tightly constrained around 26 bp for the T6, 30 bp ...

Not all DNA looks like the familiar double helix. Sometimes, parts of our genetic code fold into unusual shapes under certain conditions. One such structure known as a G-quadruplex (G4) looks like a ...